Research
Recerca
11
Jul
2023
Rare genetic disease caused by alterations to lipid metabolism
TANGO2 mutations initiate fatal metabolic crises. The gene’s role in lipid metabolism and energy production explains why.
03
Jul
2023
‘Traffic control’ system for mucin and insulin secretion identified
Findings shed light on how cells secrete just the right amount of the two proteins crucial for human health
27
Jun
2023
Researchers reveal how cells rewrite their fate
Findings can lead to new strategies to accelerate or manipulate the molecular mechanisms involved to target cancer
01
Jun
2023
DNA damage repaired by antioxidant enzymes
In crisis, the nucleus calls antioxidant enzymes to the rescue. This indicates metabolic activity, which would be a profound paradigm shift with implications for cancer research.
24
Apr
2023
Differentiation landscape of acute myeloid leukemia charted with new tool
The findings pave the way for the development of new techniques to predict how AML patients will respond to chemotherapy.
06
Apr
2023
Controversial beta cell origin theory challenged by diabetes experts
Dr. Jorge Ferrer challenges the view that adult mice form new beta cells which arise from pancreatic duct cells
06
Apr
2023
tRNA biomarkers for cancer diagnosis and prognosis enabled by new method
The new method can lead to earlier detection of diseases and improved patient outcomes
30
Mar
2023
Epigenome mapped in detail across human body
International team of CRG, Harvard, Yale, MIT, CSHL and Johns Hopkins publish personalised epigenomes of four individuals in Cell
07
Mar
2023
Heart toggles between maintenance and energy-boost mode using ribosomes
New mechanism found which can be exploited to prevent or heal damage to the heart
13
Feb
2023
Seasonal and circadian genetic variation charted across the human body
Atlas of circadian and circannual variation reveals therapeutic targets which could benefit from different doses depending on time of day and season
Pages
TANGO2 mutations initiate fatal metabolic crises. The gene’s role in lipid metabolism and energy production explains why.
Findings shed light on how cells secrete just the right amount of the two proteins crucial for human health
Findings can lead to new strategies to accelerate or manipulate the molecular mechanisms involved to target cancer
In crisis, the nucleus calls antioxidant enzymes to the rescue. This indicates metabolic activity, which would be a profound paradigm shift with implications for cancer research.
The findings pave the way for the development of new techniques to predict how AML patients will respond to chemotherapy.
Dr. Jorge Ferrer challenges the view that adult mice form new beta cells which arise from pancreatic duct cells
The new method can lead to earlier detection of diseases and improved patient outcomes
International team of CRG, Harvard, Yale, MIT, CSHL and Johns Hopkins publish personalised epigenomes of four individuals in Cell
New mechanism found which can be exploited to prevent or heal damage to the heart
Atlas of circadian and circannual variation reveals therapeutic targets which could benefit from different doses depending on time of day and season