IV CRG Annual Symposium

New challenges in the mechanistics of human disorders
CONNECTING THE GENOME WITH DISEASE

Friday, 2 December and Saturday, 3 December, 2005
Center for Genomic Regulation
Barcelona, Catalonia, Spain

Monogenic diseases research has provided knowledge about the molecular alterations that cause many severe human hereditary disorders. Despite this enormous progress, the genetic bases of common disorders that affect a large number of subjects are largely unsolved. In this symposium, we will evaluate some of the molecular mechanisms potentially involved in human disorders with special emphasis in neurological-related disorders. The symposium will bring together the best experts in the fields of small RNAs, epigenetics, genomic variation, and gene expression variation. We should evaluate to which extend these phenomena participate in the chain of events that lead to complex disorders.