PRBB-CRG Sessions
Scientific sessions of the PRBB centres funded by the Centre for Genomic Regulation (CRG) and the Barcelona Biomedical Research Park
 |
 |
 |
 |
 |
 |
28/03/202512:00MARIE CURIEPRBB-CRG SessionsDavid McCandlishCold Spring Harbor Laboratory"Understanding complex genotype-phenotype maps"Host: Nora MartinAbstract:The relationship between an organism’s genome sequence and its measurable traits and behaviors—the genotype-phenotype map—is a fundamental concept in genetics. Beyond its central role in the evolution of natural populations, understanding the genotype-phenotype map is crucial for applications such as predicting and treating genetic diseases, studying somatic evolution in cancer, advancing animal and plant breeding, and enabling protein design and synthetic biology. Recent progress in high...
04/04/202512:00MARIE CURIEPRBB-CRG SessionsAdrian BirdUniversity of Edinburgh, Wellcome Centre for Cell Biology"Proteins that interpret genomic signals to stabilize cell identity"Host: CRG PhD Community - Rabia Gul AydinAbstract:The identity of differentiated cell types is remarkably stable. This lecture will explore two ways in which this is achieved via proteins that interpret genomic signals to stabilize and optimize transcription programs. The chromatin protein MeCP2 interprets the local DNA methylation density to modulate gene expression levels in the mature brain. Loss of MeCP2 by mutation compromises neuronal function, leading...
11/04/202512:00MARIE CURIEPRBB-CRG SessionsKetan J. PatelWeatherall Institute of Molecular Medicine"DNA fragility and the chemistry of normal life"Host: Vivek MalhotraAbstract:I will discuss the fragility of DNA the blue print of life. How this fragility arises, what damages this vital molecule, and how our cells try to repair this. This repeated cycle of damage and repair drives wear and tear of the DNA molecule which ultimately leads to mutations causing our cells to be miss-instructed and become cancerous and this can also cause our cells to age. I will specifically talk about our own research which lead to the surprising discovery of how alcohol through its...
16/05/202512:00MARIE CURIEPRBB-CRG SessionsAnja GeitmannCanada Research Chair in Biomechanics of Plant Development"From microstructural features to macroscopic traits"Host: Adel Al JordAbstract:The analysis of structure-function relationships in biology must integrate features at multiple length scales. Cell morphogenetic processes occurring during plant development are crucial determinants of metabolic and mechanical functionality of mature organs. Through 4D imaging, computational modeling and micromechanical testing we can obtain a deeper understanding of the hierarchical architectural concepts underpinning metabolic processes.
20/06/202512:00MARIE CURIEPRBB-CRG SessionsAndrew HsiehFred Hutchinson Cancer Center, University of Washington"TBC"Host: Fatima Gebauer
19/09/202512:00MARIE CURIEPRBB-CRG SessionsMichael HillerLOEWE Centre for Translational Biodiversity Genomics"TBC"Host: Manuel Irimia
26/09/202512:00MARIE CURIEPRBB-CRG SessionsElinor KarlssonVertebrate Genomics Group at the Broad Institute of MIT and Harvard"TBC"Host: Donate Weghorn
03/10/202512:00MARIE CURIEPRBB-CRG SessionsChristina LeslieMemorial Sloan Kettering Cancer Center"TBC"Host: Fanny Mollandin & Jorge Ferrer
31/10/202512:00MARIE CURIEPRBB-CRG SessionsKristen VerheyUniversity of Michigan Medical School"TBC"Host: Thomas Surrey
14/11/202512:00MARIE CURIEPRBB-CRG SessionsAlexander van OudenaardenHubrecht Institute"TBC"Host: Renee Beekman