CRG Core Facility Technology Symposium: Innovative approaches for imaging and analysis
17/11/2011
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CRG Core Facility Technology Symposium: Innovative approaches for imaging and analysis
Barcelona, Spain
Advanced microscopy and imaging methods have made significant advances in the last years. This technology seminar is going to highlight recent developments in three important areas, label development, automated high content imaging and analysis, molecular Imaging and 3D visualization technologies.
The properties of switchable fluorophores are absolutely fundamental for imaging below the diffraction limit in super-resolution light microscopy and the development of improved labels is therefore one of the most active areas of light nanoscopy research. Prof. Stefan Jakobs recently developed fluorescent proteins optimized for multiple reversible switching and excitation decoupled switching which he will present.
Analysis of cellular properties requires data from a large number of cells. The data acquisition can be very time-consuming if the process of interest can only be found in a subset of cells or during certain phases of the cell cycle. Automated high content imaging helps in increasing the number of datasets and is even further improved by automated recognition and selection of suitable cells during the image acquisition. Dr. Christian Conrad will present the software “Micropilot” capable of automatically selecting cells of interest and initiating complex experiments in the selected regions.
Nowadays three dimensional imaging modalities such as CT, MRI and 3D ultrasound play an ever increasing role in research, diagnosis and treatment planning. The Erasmus MC was the first university medical center to install an I-Space fully immersive virtual reality (VR) system which allows very detailed three dimensional volume visualizations of gene and protein expression in small tissue samples, using confocal microscopy (CSLM) or optical projection tomography (OPT), enabling new insights into the developmental processes of both model organisms as well as humans. Dr. Andreas Kremer will provide an overview of these technologies and their uses in translational research.
Speakers
Christian CONRAD, Bioquant / German Cancer Research Center Heidelberg, Heidelberg DE
Stefan JAKOBS, Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Göttingen DE
Andreas KREMER, Department of Bioinformatics, Erasmus University Medical Center, Rotterdam NL
Christian CONRAD, Bioquant / German Cancer Research Center Heidelberg, Heidelberg DE
Stefan JAKOBS, Department of NanoBiophotonics, Max Planck Institute for Biophysical Chemistry, Göttingen DE
Andreas KREMER, Department of Bioinformatics, Erasmus University Medical Center, Rotterdam NL
Organizers
Timo Zimmermann (visit the Advanced Light Microscopy Unit)
Renza Roncaratti (visit the High-Throughput Screening Unit)
Doris Meder (visit the CRG Core Facilities main page)
Timo Zimmermann (visit the Advanced Light Microscopy Unit)
Renza Roncaratti (visit the High-Throughput Screening Unit)
Doris Meder (visit the CRG Core Facilities main page)
Venue
Ramón y Cajal meeting room
CRG - Centre for Genomic Regulation
Dr. Aiguader, 88
08003 Barcelona, Spain
www.crg.eu
Registration
Participation to the symposium is free of charge and open to all PRBB staff as well as external scientists.
This symposium is limited to 70 participants (registrations will be managed on a first come, first served basis).
Registration for this event is now closed.
Contact person
Blanka Wysocka
CRG - Centre for Genomic Regulation
Dr. Aiguader, 88
08003 Barcelona, Spain
Tel. +34 93 316 01 45
Fax +34 93 316 00 99
Language: All lectures will be in English
