Annual Meeting "Chromosomes, Stem Cells and Disease" & Satellite Workshop “Modeling 3D-Structure of Chromosomes”
20/09/2012 to 22/09/2012
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Annual Meeting "Chromosomes, Stem Cells and Disease" & Satellite Workshop “Modeling 3D-Structure of Chromosomes”
Barcelona, Spain
“Chromosomes, Stem Cells and Disease” Meeting
20-21 September 2012
Organizers: Miguel Beato (CRG), Luciano di Croce (CRG), Marc Martí-Renom (CNAG-PCB)
The “Chromosomes, Stem Cells and Disease” meeting will be held at the Center for Genomic Regulation (CRG) in Barcelona on the September 20-21, 2012. This exciting 2-day conference will bring together scientists studying chromatin structure, stem cell and epigenetics. The talks will cover a broad range of topics, including chromosome organization, long-range interactions, chromatin assembly, stem cell regulation/differentiation, RNA-based mechanisms and transcription regulation. Young scientists will be able to present their work through posters (click here to download the list of accepted posters) or through high number of short talks selected from submitted abstracts. The programme includes time for exchanging ideas and discussing novel hypothesis at the end of each session, and time for the informal interactions.
Confirmed Speakers
- Eduard BATLLE, Colorectal cancer laboratory, Oncology, Institute for Research in Biomedicine (IRB), Barcelona ES
- Neil BROCKDORFF, Developmental Epigenetics, Department of Biochemistry, University of Oxford, UK
- Giacomo CAVALLI, Chromatin and Cell Biology, Institute of Human Genetics, Montpellier FR
- Job DEKKER, Biochemistry & Molecular Pharmacology, University of Massachusetts Medical School, Worcester (MA) US
- Thomas GRAF, Gene Regulation, Stem Cells and Cancer Programme, CRG, Barcelona ES
- Tony KOUZARIDES, Gurdon Institute and Department of Pathology, University of Cambridge, UK
- Peter FRASER, Nuclear Dynamics and Function Laboratory, The Babraham Institute, Cambridge UK
- Kristian HELIN, Biotech Research and Innovation Centre (BRIC), Centre for Epigenetics, University of Copenhagen, DK
- Leonid MIRNY, Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge (MA) US
- Paola SCAFFIDI, Cell Biology of Genomes Group, National Cancer Institute, NIH, Bethesda (MD) US
- Guy SAUVAGEAU, Molecular Genetics of Stem Cells Laboratory, Institute of Research in Immunology and Cancer (IRIC), University of Montreal, CA
- Yang SHI, Department of Pathology, Harvard Medical School & Division of Newborn Medicine, Department of Medicine, Children’s Hospital, Boston (MA) US
- Ramin SHIEKHATTAR, Gene Expression and Regulation, The Wistar Institute, Philadelphia (PA) US
- Anton WUTZ, Epigenetic Regulation and Cell Identity Control, Department of Biochemistry, University of Cambridge, UK
Click here to download the list of accepted posters.
Click here to download the final schedule of the meeting.
Venue
PRBB Auditorium
Dr. Aiguader 88
08003 Barcelona
Spain
Registration:
Registration is now closed. The accepted participants and posters (when applicable) will be notified on 25 June. Accepted participants will be asked to pay a registration fee of 50 EUR.
Contact person:
Blanka Wysocka
CRG - Centre for Genomic Regulation
Dr. Aiguader, 88
08003 Barcelona, Catalonia, Spain
Tel.: +34 93 316 01 45
Activity Supported by: Active Motif
The meeting is cofunded by the Consolider-Ingenio 2012 project, ref. CSD2006-00049.
****************The meeting will be followed by the next satellite workshop:
Satellite Workshop: “Modeling 3D-Structure of Chromosomes”
21-22 September 2012
Organizers: Miguel Beato (CRG), Luciano di Croce (CRG), Marc Martí-Renom (CNAG-PCB)
The genome undergoes several layers of compaction in order to be accommodated into the nucleus. At the most basic level, the DNA is assembled by wrapping 146 base pairs (that is, approximately 1.7 super-helical turns of the double helix) around a histone octamer to form the classic beads on a string nucleosomal fiber, which is further compacted to form the 30 nm chromatin fibre by interactions between nucleosomes and with linker histones. At this level of structure, a considerable amount is known about the effects of DNA methylation, histone modifications and chromatin remodeling on critical nuclear processes. Beyond this level of compaction, the chromatin fiber is folded and coiled eventually reaching the recognizable chromosomal form, a total compaction of 300,000 fold. Almost nothing is known about how such folding is controlled, but recent discoveries clearly indicate that this folding and compaction is non-random. The goal of the proposed workshop is to bring together leading investigators to discuss the critical topics of nuclear compartmentalization, higher-order chromosome organization, and 3D modeling of genomes.
Confirmed Speakers
- Kerstin BYSTRICKY, Chromatine et expression génique, Laboratoire de Biologie Moléculaire Eucaryote (LBME), Université de Toulouse, CNRS, Toulouse FR
- Victor CORCES, O. Wayne Rollins Research Center, Emory University, Atlanta (GA) US
- Job DEKKER, Biochemistry & Molecular Pharmacology, University of Massachusetts Medical School, Worcester (MA) US
- Dieter HEERMANN, Statistical Physics and Theoretical Biophysics Group, Institut für Theoretische Physik, Heidelberg University, DE
- Ernest LAUE, Structural and molecular cell biology, Department of Biochemistry, School of the Biological Sciences, University of Cambridge, UK
- Yolanda MARKAKI, LMU Biocenter, Department of Biology II, Anthropology and Human Genetics, Ludwig Maximilians University, Martinsried DE
- Leonid MIRNY, Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge (MA) US
- Ana POMBO, Genome Function Group, MRC Clinical Sciences Centre, Imperial College School of Medicine, London UK
- Angelo ROSA, Scuola Internazionale Superiore di Studi Avanzati (Sissa/Isas), Trieste IT
- Mariliis TARK-DAME, Swammerdam Institute for Life Sciences, University of Amsterdam, NL
The workshop is cofunded by the Consolider-Ingenio 2012 project, ref. CSD2006-00049.
Venue
Marie Curie meeting room
Dr. Aiguader 88
08003 Barcelona
Spain
Registration
Registration is now closed. The accepted participants will be notified on 19 June. Accepted participants will be asked to pay a registration fee of 30 EUR.
Registration is now closed. The accepted participants will be notified on 19 June. Accepted participants will be asked to pay a registration fee of 30 EUR.
Contact person
Blanka Wysocka
CRG - Centre for Genomic Regulation
Dr. Aiguader, 88
08003 Barcelona, Catalonia, Spain
Tel.: +34 93 316 01 45
